Associate Professor of Teaching
Associate Head, Undergraduate
CHBE 403

Research Summary

Thermodynamics and kinetics of protein stability and protein-ligand binding


University of California, Berkeley, 1992, Ph.D.
University of California, Berkeley, 1985, M.S.
University of Alberta, 1983, B.A.Sc.

Research interests + projects

Dr. Creagh research interests include thermodynamics and kinetics (calorimetry, analytical ultracentrifugation, surface plasmon resonance) of protein stability and protein-ligand binding.

Scholarly and professional activities + affiliations

Selected publications + presentations

B. Lai, A.L. Creagh, J. Janzen, C.A. Haynes, D.E. Brooks, J. Kizhakkedathu, “The induction of thrombus generation on nanostructured neutral polymer brush surfaces”, Biomaterials 31 6710-6718 (2010).

J. Kizhakkedathu, A.L. Creagh, R.A. Shenoi, N.A.A. Rossi, D.E. Brooks, T. Chan, J. Lam, S.R. Dendappally, C.A. Haynes, “High molecular weight polygycerol-based multivalent mannose conjugates”, Biomacromolecules, 11 (10) 2567-2575 (2010).

M. Foldvari, I. Badea, S. Wettig, D. Baboolal, P, Kumar, A. L. Creagh, C. A. Haynes, “Topical delivery of interferon alpha by biphasic vesicles: evidence for a novel nanopathway across the stratum corneum”, Mol. Pharmaceutics, 7 (3) 751-762 (2010).

M. Kavoosi, A.L. Creagh, R.F.B. Turner, D.G. Kilburn, C.A. Haynes, “Direct measurement of the kinetics of CBM9 fusion-tag bioprocessing using luminescence resonance energy transfer”, Biotech. Prog. 25 (3) 874-881 (2009).

A.-K. Bordbar, A.L. Creagh, F. Mohammadi, C.A. Haynes, C. Orvig, “Calorimetric studies of the interaction between the insulin-enhancing drug candidate bis(maltolato)oxovanadium(IV) (BMOV) and human serum apo-transferrin”, J. Inorg. Biochem., 103 643-647 (2009).